If fishing streams, water will be clear and lower meaning fish generally more skittish. Thus accuracy of casting as bigger fish will generally hold in the better but harder lies (bush, undecut banks etc.). I love nymphs (Zaks!) so would have a good range of sizes plus some lighter tippet material for that finesse fishing.
If fishing bigger dams with good food source, bigger flies (wolly buggers black & orange / dragonfly nymphs filoplume) would do the trick. Heavier tippet material as some good fish around generally. Quick retrieves if fish are in spawning stage as they are agressive.
when fishing the underburg region I found a small Mepps works wonders